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Influence of LPS modifications on OMVs production

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Our paper in j. Bact is online (not proof edited):

PmrC/EptA and CptA negatively affect outer membrane vesicle production in Citrobacter rodentium.

I am thankful for this nice last collaboration with a talented researcher Hervé le Moual, and congratulation to the amazing student Anshul Sinha (and Sammy Nyongesa)!!!!

 

2018 Institut Pasteur International Network Symposium

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A really great moment of scientific excitation with all the IP network all around the globe!

 

2018 International Pathogenic Neisseria Conference

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We will be present at the 2018 International Pathogenic Neisseria Conference

We will show our work on Monday and Thursday

Study of cell-shape diversity and evolution inside the Neisseriaceae family as a way to reveal new cellular functions.

Anti-Neisseria drugs screening start revealing the Achilles’ heel of N. meningitidis and N.
gonorrhoeae.

and I will moderate the Anti-Microbial Resistance and Therapies session the morning of Friday, Sept. 28.

New article: The mycobacterial cell envelope: a relict from the past or the result of a recent evolution?

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Our new article asking about the origins of the mycobacterial cell envelope just get accepted. You can find the article here

Do not hesitate to contact me if you want to debate about these hypotheses 😉

New article describing the only lytic phages known to infect the spirochete Leptospira

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With our colleagues of the Institut Pasteur Paris we sequenced and analysed the first genomes of the lytic phages LE3 and LE4 that can infect the saprophyte Leptospira biflexa using the lipopolysaccharide O-antigen as receptor. Bioinformatics analysis showed that the 48-kb LE3 and LE4 genomes are similar and contain 62% genes whose function cannot be predicted.

Read the full paper online here

Figure 1

Figure 1

Transmission electron micrographs of leptophages. Morphology of leptophages (A) LE1, (B) LE3, and (C) LE4. Scale bar represents 100 nm. (D) Magnification of L. biflexa strain Patoc 1 (cell length of 10 µm) six hours after infection with phage LE4 (MOI=10). Arrowheads indicate representative phages. Scale bar represents 200 nm.

 

Entretiens Jacques Cartier

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Le programme provisoire des entretiens Jacques Cartier est en ligne. RDV le Lundi 12 Nov. à Clermont-Ferrand (France). Plusieurs  chercheurs de l’INRS feront le déplacement: Voyez le programme de notre symposium ici

Félicitations à Antony Vincent pour ses 2 bourses de postdoc!!!! (et merci au FRQNT/CRSNG)

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Félicitations à Antony pour ces deux bourses qui récompensent ton super travail!!!

Ces bourses vont permettent l’étude détaillée de l’évolution des Leptospires.

Bourse Postdoctorale:

Postdoctoral Fellowships (PDF) from NSERC and Postdoctoral research scholarship (B3X) from FRQNT